Chest pain is unsettling, and when it seems connected to how poorly you’ve been sleeping, it’s natural to wonder whether the two are linked. Can a lack of sleep cause chest pain? Yes, it can. Sleep deprivation affects your body in ways that go well beyond tiredness, and several of those effects can produce genuine discomfort in the chest.
Here, Dr. Aditi Desai, President of the British Society of Dental Sleep Medicine, explains why lack of sleep can cause chest pain, what role sleep apnoea might play, and when it’s time to seek help.
How Lack of Sleep Can Cause Chest Pain
There isn’t a single explanation for why a lack of sleep cause chest pain. Instead, poor sleep triggers a range of changes in your body, each capable of contributing to discomfort in the chest.
Stress Hormones and Cardiovascular Strain
During healthy sleep, your heart gets a period of recovery. Heart rate slows, blood pressure drops, and breathing stabilises. When you don’t sleep enough, this recovery window disappears.
Poor sleep raises cortisol and adrenaline levels, shifting your nervous system toward a sustained state of heightened alertness. Blood pressure stays elevated for more hours per day, and your heart has to work harder to keep up. This constant cardiovascular strain is one of the main ways lack of sleep can cause chest pain, producing tightness, palpitations, and a general sense of pressure.

Muscle Tension and Chest Wall Discomfort
When your body runs on insufficient sleep, stress hormones increase muscle tension throughout the body, including the muscles of the chest wall. This can produce a dull ache or sharp, localised pain, particularly around the sternum and ribs.
Sleep also serves as a natural period of muscle recovery and relaxation. Without it, existing tension accumulates. If you’re already prone to costochondritis (inflammation where the ribs meet the breastbone), poor sleep can make the discomfort noticeably worse. So can a lack of sleep cause chest pain from muscle tension alone? Absolutely.
Acid Reflux and GERD
The relationship between poor sleep and gastro-oesophageal reflux disease (GERD) runs in both directions. Sleep deprivation increases sensitivity in the oesophagus, meaning you feel reflux symptoms more intensely. At the same time, lying flat reduces the gravitational barrier that normally keeps stomach acid in place, and swallowing frequency drops during sleep, removing another natural defence.
GERD-related chest pain can feel remarkably similar to cardiac pain. It often presents as a burning or pressing sensation behind the breastbone, sometimes radiating to the neck or back. If your chest pain worsens when lying down and improves with antacids, reflux aggravated by poor sleep is a likely contributor. It’s another way that lack of sleep cause chest pain that many people don’t expect.
Heightened Pain Sensitivity
One of the less obvious effects of poor sleep is that it lowers your pain threshold. Research has shown that even short periods of sleep loss impair the body’s ability to dampen pain signals, while also increasing sensitivity to stimuli that would normally go unnoticed.
In practical terms, this means minor chest wall tension or mild reflux that wouldn’t bother you after a good night’s rest becomes amplified into noticeable chest pain when you’re sleep deprived. Can a lack of sleep cause chest pain simply by making you more sensitive to it? Yes, and this is more common than most people realise.
Anxiety and Panic Responses
Poor sleep and anxiety reinforce each other. The less you sleep, the more vulnerable you become to anxious thoughts and physical tension. The more anxious you feel, the harder it is to fall asleep.
Anxiety commonly produces chest symptoms: tightness, sharp stabbing sensations, a feeling of heaviness, or palpitations. These are driven by rapid, shallow breathing, increased heart rate, and sustained muscle tension. If you’re experiencing chest pain alongside difficulty sleeping and rising anxiety, the two are very likely connected. Stress management for better sleep is often an essential part of treatment.
The Connection Between Sleep Apnoea and Chest Pain
If you snore heavily, wake up gasping, or feel exhausted despite spending enough hours in bed, sleep apnoea may be contributing to your chest pain. Obstructive sleep apnoea causes repeated airway collapse during sleep, and the consequences go far beyond snoring.
Each time the airway closes, oxygen levels drop and the body mounts a stress response, releasing adrenaline and driving sudden surges in heart rate and blood pressure. These episodes, which can happen dozens of times per hour, place significant strain on the cardiovascular system. Published case reports have documented patients whose chest pain was initially investigated as cardiac angina before untreated sleep apnoea was identified as the underlying cause.
The mechanical effects also matter. When you try to breathe against a closed airway, the chest generates extreme negative pressure. This distorts the chest wall and impairs normal cardiac function temporarily. It’s a direct source of chest discomfort, often worst at night or shortly after waking.
There’s also a strong link between sleep apnoea and GERD. The intense pressure changes during apnoea episodes can pull stomach acid back into the oesophagus, worsening reflux symptoms and adding another source of health problems linked to sleep apnoea. The relationship between sleep apnoea and heart health is well established, and chest pain is one of the symptoms that should prompt further investigation.
How to Reduce Chest Pain Linked to Poor Sleep
Now that you understand how lack of sleep can cause chest pain, what can you do about it? Addressing the underlying sleep problem is the most effective approach.
Prioritise consistent sleep. Going to bed and waking up at the same time each day helps regulate your circadian rhythm, lowers baseline cortisol levels, and gives your cardiovascular system the nightly recovery period it needs.
Talk to a specialist about your sleep. If you snore, wake with headaches, or experience excessive daytime fatigue, a professional assessment can determine whether sleep apnoea is driving your symptoms. A specialist can recommend the right treatment for your situation, whether that’s a mandibular advancement device, lifestyle changes, or another approach.
Elevate the head of your bed. If acid reflux is contributing to your chest pain, raising the head end of your bed by 15 to 20 centimetres can reduce night-time reflux episodes significantly. Avoid eating within two to three hours of bedtime.
Manage stress and anxiety. Breathing exercises, regular physical activity, and structured relaxation techniques all help reduce the muscle tension and hormonal imbalance that contribute to chest discomfort. If anxiety is severe, seek professional support alongside addressing your sleep.

Frequently Asked Questions
Can a lack of sleep cause chest pain and tightness?
Yes. Poor sleep raises stress hormones, increases muscle tension, and elevates blood pressure, all of which can produce a feeling of tightness or pressure in the chest.
Is chest pain from lack of sleep dangerous?
It depends on the cause. While sleep-related chest pain is often musculoskeletal or reflux-based, it can also signal cardiovascular strain or undiagnosed sleep apnoea. A specialist assessment can help identify the cause and the right treatment.
Can lack of sleep cause chest pain that feels like a heart problem?
Yes. Several of the ways lack of sleep cause chest pain, including acid reflux, cardiovascular strain, and anxiety responses, can produce symptoms that feel similar to cardiac pain. A proper evaluation is important to determine the actual cause.
Your Next Step
If you’re experiencing chest pain alongside poor sleep, heavy snoring, or daytime exhaustion, it’s worth investigating whether a sleep disorder is involved. Dr. Aditi Desai is the President of the British Society of Dental Sleep Medicine and offers comprehensive sleep assessments and personalised treatment plans, including oral appliance therapy, at her London practices.
Book a consultation to discuss your symptoms and explore your options.



